Pathogenic viruses are ideal systems for studying evolution, with their large population sizes, high mutation rates, short generation times, and near-replicate natural experiments in different infections. At the same time, evolution and population genetics are some of our best lenses for answering practically important questions about viral spread and dynamics.
- Koelle et al (2022), Masks Do No More Than Prevent Transmission: Theory and Data Undermine the Variolation Hypothesis
- Ghafari et al (2022), Investigating the evolutionary origins of the first three SARS-CoV-2 variants of concern
- Scherer et al (2022), SARS-CoV-2 Evolution and Immune Escape in Immunocompromised Patients
- Allman, Koelle, and Weissman (2021), Heterogeneity in viral infections increases the rate of deleterious mutation accumulation
- Ghafari et al (2020), Inferring transmission bottleneck size from viral sequence data using a novel haplotype reconstruction method
- Li et al (2019), Why are CD8 T cell epitopes of human influenza A virus conserved?
- Sobel Leonard et al (2017), Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus, and see correction